Top College Football Betting Picks and Predictions: Week 11

Top College Football Betting Picks and Predictions: Week 11

By Michael Thornton

February 28, 2025 at 07:05 PM

Week 11 of college football features several crucial matchups with significant betting opportunities. Here are the top picks for this week's games:

Purdue vs. Illinois (-6.5)

  • Illinois enters as clear favorites with star RB Chase Brown (1,344 rushing yards)
  • Purdue (5-4) coming off a blowout loss to Iowa
  • Illinois' strong secondary matches up well against Purdue's pass-heavy offense
  • Prediction: Take Illinois -6.5

Indiana (+40) vs. Ohio State

  • Ohio State struggled last week against Northwestern despite remaining undefeated
  • Buckeyes winning by average of 30 points per game
  • Indiana's underdog status makes them dangerous with nothing to lose
  • Prediction: Take Indiana +40

TCU (+7.5) vs. Texas

  • TCU ranked in CFP Top 4 but still underdogs against 6-3 Texas
  • QB Max Duggan leading TCU's explosive offense (24 TDs, 2 INTs)
  • Texas showing improvement with QB Quinn Ewers but defense remains inconsistent
  • Prediction: Take TCU +7.5

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These picks are based on recent team performance, head-to-head matchups, and key player statistics. While favorites like Illinois and Ohio State should win their games, the point spreads create valuable betting opportunities on underdogs.

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